Parathyroid hormone and bone histology: Response to hypocalcemia in osteitis fibrosa
نویسندگان
چکیده
منابع مشابه
Generalized Osteitis Fibrosa with Parathyroid Adenoma
or disseminated sclerosis but I was told that she had had some pain around the groin, that her doctor had sent her for X-ray of the pelvis, and that a large destructive lesion had been found in one of the pubic rami. A surgeon saw her and advised that she should be admitted to a chronic hospital: the diagnosis was secondary tumours of bone. When I first looked at this X-ray picture of the pubis...
متن کاملParathyroid hormone 7-84 induces hypocalcemia and inhibits the parathyroid hormone 1-84 secretory response to hypocalcemia in rats with intact parathyroid glands.
Biologic effects of large C-terminal parathyroid hormone (PTH) fragments, opposite to those of N-terminal PTH, have been demonstrated. C-terminal PTH fragments are co-secreted with N-terminal PTH from the parathyroids. The aim of our study was to examine whether C-terminal PTH 7-84 regulates secretion of PTH 1-84 and affects the expression of genes of relevance for parathyroid function, PTH, ca...
متن کاملThe influence of acute and chronic hypercalcemia on the parathyroid hormone response to hypocalcemia in rabbits.
OBJECTIVE To investigate the influence of acute and chronic hypercalcemia on the parathyroid hormone (PTH) response to hypocalcemia. DESIGN The PTH response to hypocalcemia has been evaluated in three groups of rabbits: Group I, normal rabbits, Group II, normal rabbits subjected to an acute hypercalcemic clamp (induced by CaCl(2) infusion) and Group III, rabbits with chronic hypercalcemia (du...
متن کاملBoth duration and degree of hypercalcemia influence the reduced parathyroid hormone response to hypocalcemia after hypercalcemia.
The stimulation of parathyroid hormone (PTH) secretion by hypocalcemia is reduced when hypocalcemia is preceded by hypercalcemia. The present study investigates whether the duration and degree of hypercalcemia influence the reduced PTH response to hypocalcemia after hypercalcemia. In addition, the implication of the arachidonic acid (AA) signaling pathway in this effect is evaluated. The PTH re...
متن کاملOsteitis Fibrosa Cystica Mistaken for Malignant Disease
A 65-year-old man with back pain had plain radiographs that showed multiple osteolytic bone lesions of the pelvis, femur and L-spine; an magnetic resonance imaging scan of the L-spine showed extensive bony resorption with a posterior epidural mass involving the L1 spinous process; these findings suggested multiple myeloma or bony metastasis. However, all serology testing was negative. The parat...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1984
ISSN: 0085-2538
DOI: 10.1038/ki.1984.37